Revision history for Comparison study


Revision [168]

Last edited on 2015-05-26 12:24:18 by dbhaskar92 [added graph]
Additions:
- Tissue height/width (μm) vs. time (hrs) Measured by distance between largest center of mass and lowest
- Number of cell-cell interfaces vs. time (hrs)
Deletions:
- Tissue height/width (μm) vs. time (hrs) Measured by distance between largest center of mass and lowest.


Revision [167]

Edited on 2015-05-26 10:38:47 by dbhaskar92 [added few graph ideas]
Additions:
Pick a fixed duration cell cycle. Check for growth anisotropy.

Graphs:
- Number of cells vs. time (hrs)
- Numbers of cells at generation _ vs. time (hrs)
- Avg. cell area (μm^2) vs. time (hrs)
- Tissue height/width (μm) vs. time (hrs) Measured by distance between largest center of mass and lowest.
Graphs:
- All of the above
- Number of inhibited cells vs. time (hrs)
Deletions:
Pick a fixed duration cell cycle. Check for anisotropy.


Revision [166]

Edited on 2015-05-26 10:26:19 by dbhaskar92 [update research questions]
Additions:
**Step 2) Cell division with contact inhibition**
**Step 3) External force calibration**
Once space and time are calibrated, external force can be calibrated in non-inertial motion of cells. We can define a unit of external force as the amount of model specific force required to move a cell with center of mass at (0 μm, 0 μm) to (5 μm, 0 μm).
**Step 4) Cell-cell and cell-ECM adhesion**
**Step 5) A comparative study**
Examples: cell sorting, tissue invasion, wound healing assay, tissue folding, collective migration, rosette formation, etc.
** Research Questions:**
Does the rate of cell sorting and wound healing depend on choice on model?
Does greater flexibility in cell shape representation lead to more realistic tissue folding/invagination?
Can rosette formation be achieved using only cell polarity and external forces?
Deletions:
**Step 2) Cell division with contact inhibition **
**Step 3) Cell-cell and cell-ECM adhesion**
**Step 4) Cell division in confined space**
**Step 5) Cell sorting, tissue invasion, wound healing assay, tissue folding experiments**
Once everything is calibrated, we can do experiments to compare all models!


Revision [159]

The oldest known version of this page was created on 2015-05-19 10:47:45 by dbhaskar92 [update research questions]
Valid XHTML :: Valid CSS: :: Powered by WikkaWiki